Present And Future of Mesenchymal Stem Cells In Rheumatology

Haematopoietic stem cells and mesenchymal stem cells as tools for present and future cellular therapies.

Postnatal stem cells are present in many adult tissues, and are thought to ensure homoeostasis by replacing functionally declining cells by newly differentiated ones. Postnatal stem cells used as such or after in vitro manipulation hold out strong hopes for reconstructive therapies. For instance, the grafting of native haematopoietic stem cells (HSC) restores haematopoiesis in genetically defic...

Rheumatology, past, present and future.

Mesenchymal stromal cells: past, present, and future.

Adult mesenchymal stromal cells are plastic-adherent cells that are self-renewing and have the capacity to differentiate into various tissue specific lineages. Stromal cells were initially discovered over 100 years ago and substantial insight into stromal cell identification, isolation, characterization, and differentiation has been made, including efforts to elucidate the factors involved in s...

Application of Nanoscaffolds and Mesenchymal Stem Cells in Tissue Engineering

Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...

Stem Cells Treatment: Past, Present and Future

Alberto Gobbi, Mudhigere Abhishek & Georgios Karnatzikos In view of high costs and complexities involved in the treatment of OA, current trend in research is moving towards preventive interventions and therapeutic solutions that can lead to an enhancement of tissue regeneration and reduction of degenerative mechanisms. The number of people with OA disability is expected to double by the year 20...